Search Results
| Date | Team | Acquired | Relinquished | Notes |
| 2021-12-02 | Saints | • Tanoh Kpassagnon | placed on IR with ankle injury | |
| 2021-12-03 | Giants | • Trent Harris | placed on IR with ankle injury | |
| 2021-12-04 | 49ers | • Trey Sermon | placed on IR with ankle injury | |
| 2021-12-07 | Washington | • Khaleke Hudson | placed on IR with ankle injury | |
| 2021-12-08 | Raiders | • Kenyan Drake | placed on IR with surgery on right ankle to repair fracture | |
| 2021-12-08 | Raiders | • Nick Kwiatkoski | placed on IR with ankle injury | |
| 2021-12-11 | 49ers | • Emmanuel Moseley | placed on IR with high ankle sprain | |
| 2021-12-11 | Chiefs | • Chris Lammons | placed on IR with ankle injury | |
| 2021-12-11 | Titans | • Tommy Hudson | placed on IR with ankle injury | |
| 2021-12-11 | Washington | • Wes Schweitzer | placed on IR with ankle injury | |
| 2021-12-16 | Bengals | • Riley Reiff | placed on IR with left ankle injury | |
| 2021-12-16 | Patriots | • Ronnie Perkins | placed on IR with ankle injury | |
| 2021-12-18 | Titans | • Tory Carter | placed on IR with ankle injury | |
| 2021-12-21 | Jaguars | • Rayshawn Jenkins | placed on IR with fractured ankle | |
| 2021-12-28 | Rams | • Ernest Jones (b) | placed on IR with left high ankle sprain | |
| 2021-12-29 | Bears | • Jalen Tabor / Teez Tabor | placed on IR with ankle injury | |
| 2021-12-29 | Texans | • Phillip Dorsett II | placed on IR with ankle/foot injury | |
| 2021-12-29 | Vikings | • Adam Thielen | placed on IR with left ankle injury | |
| 2021-12-31 | Browns | • John Kelly Jr. | placed on practice squad IR with ankle injury | |
| 2022-01-03 | Texans | • Grayland Arnold | placed on IR with ankle injury | |
| 2022-01-03 | Titans | • MyCole Pruitt | placed on IR with surgery on ankle | |
| 2022-01-04 | Jets | • Bryce Huff | placed on IR with ankle injury | |
| 2022-01-06 | Bears | • Jakeem Grant | placed on IR with ankle injury | |
| 2022-01-12 | Rams | • Jordan Fuller | placed on IR with ankle injury | |
| 2022-08-15 | Buccaneers | • Kenjon Barner | placed on IR with ankle injury |
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